What happens when a non-profit's website grows in reach and effectiveness to the point where it eclipses all other activities of that organization? This isn't a hypothetical question: many non-profits, if they took a dispassionate survey of their various activities (web, books, conferences, meetings), and truly weighed the effectiveness of the web (which routinely reaches tens of thousands) and other programs (which generally reach far fewer) would come to the conclusion that the web is possibly the only thing the organization should focus on.
So what does a dot-org look like that focuses only on the web? It looks like a dot-com: eBay, for example, has an entire organization built up to care for and feed a web site. Sure, eBay hosts conferences, and prints publications, and holds meetings, but the principal identity of eBay is the web. Similarly, the principal identity of most non-profits should be (and likely will be) the web. This will represent a dramatic psychological transition for organizations, but any review of web metrics and trends makes it clear -- most non-profits will be eaten by their websites, if they haven't been already.